Site icon New

MCQ – 90083

Question

Which of the following drugs shown in the graph below has highest potency
A. Drug A
B.

Drug B

C.

Drug C

D.

Both Drugs A and B

Show Answer

Correct Answer � A

Explanation

Answer A)

In Log DRC, More the curve is on the left side, more potent is the drug

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

 A highly potent drug (e.g., fentanyl, alprazolam, risperidone) evokes a given response at low concentrations, while a drug of lower potency (meperidine, diazepam, ziprasidone) evokes the same response only at higher concentrations. Higher potency does not necessarily mean more side effects

Schematic illustration of the dose-response curves for a series of agonists (A, B, C and D) that have the same efficacy, but differ in terms of their potency. The most potent drug (Drug A) has the lowest EC50 value, and is approximately 20-30 fold more potent than Drug D.

Exit mobile version