Graph showing three drugs A, B & C. Which of the following drugs shown in the graph below has the highest potency?
Both Drug A & B
Ans: A. Drug A
The line on the left is more potent.
Drug A is more potent.
- The position of DRC on the dose axis is the index of drug potency which refers to the amount of drug needed to produce a certain response.
- A DRC positioned rightward indicates lower potency.
- Relative potency is often more meaningful than absolute potency and is generally defined by comparing the dose (concentration) of the two agonists at which they elicit a half-maximal response (EC 50 ).
- Drug potency is clearly a factor in choosing the dose of a drug.