OCD-Management & prognosis
Management:
Pharmacotherapy:
- First Line – SSRIs and Clomipramine [adverse side effect profile]
- If first line fails then antipsychotics [Haloperidol, quetiapine, risperidone, olanzapine]
- Other Drugs [Venlafaxine, Lithium, valproate and carbamazepine]
Psychotherapy:
- Cognitive Behavior therapy [Exposure & Response prevention]
- Desensitization, thought stopping, flooding and aversive conditioning
Other T/T modalities – ECT, Psychosurgery [Cingulotomy, capsulotomy – Caudate tractotomy]
Prognosis:
Acute Onset – 50%. 20-30% Significant improvement, 40-50% moderate, rest may so deterioration
