Tag: neurotransmitter

Bipolar disorder-Etiology


Bipolar disorder-Etiology


The etiology of bipolar disorder is influenced by the following 2 factors:

Neurotransmitter:

  • Increased level of dopamine in pathophysiology of Manic episode
  • For Depression Serotonin and NE

Genetic Factors:

  • Chromosome 18q and 22q has strongest linkage to bipolar disorder
  • Chromosome 21q has also been implicated
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