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Image Based Question-65323

Question

Typical bodies seen in Ovarian cell follicles (in this picture marked by a circle) is found in:

A. Dysgerminoma.

B. Theca cell tumour.

C. Granulosa cell tumor.

D. Arrhenoblastoma.

 

Show Answer

Correct Answer » C

Explanation

The space marked by a circle in the image is composed of  Call Exner bodies

Answer is C.)Granulosa cell tumor 

Call–Exner bodies are small eosinophilic fluid-filled spaces between granulosa cells.

  • The granulosa cells are usually arranged haphazardly around the space.
  • They are pathognomonic for Granulosa cell tumors.
  • They are composed of membrane-packaged secretion of granulosa cells.

Granulosa cell tumours (or granulosa-theca cell tumours) are tumours that arise from granulosa cells.

  • These tumours are part of the sex cord-gonadal stromal tumour or non-epithelial group of tumours.
  • Although granulosa cells normally occur only in the ovary, granulosa cell tumours occur in both ovaries and testicles.
  • These tumours should be considered malignant .
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