A. It is an exclusive human pathogen.
B. Some strains may cause disseminated disease.
C. Acute urethritis is the most common manifestation in males.
D. All strains are highly sensitive to penicillin.
Ans:All strains are highly sensitive to penicillin.
The micro-organism shown in the photomicrograph above represents Neisseria gonorrhoea.
- Gonorrhea is a purulent infection of the mucous membrane surfaces caused by Neisseria gonorrhoeae.
- N gonorrhoeae is spread by sexual contact or through transmission during childbirth. It is an exclusive human pathogen.
- In women, the cervix is the most common site of gonorrhea, resulting in endocervicitis and urethritis, which can be complicated by pelvic inflammatory disease (PID). In men, gonorrhea causes anterior urethritis.
- Gonorrhea can also spread throughout the body to cause
- localized(conjuctivitis,arthritis,endocarditis,meningitis) and disseminated disease(disseminated gonococcal infection (DGI)) .
- Gram-negative cocci that typically appear in pairs with the opposing sides flattened (a “kidney bean” appearance).
- Penicillin is ineffective in treatment of gonorrhoea as most of the strains are resistant to penicillin because penicillnase producing N. gonorrhoeae (PPNG) have spread widely.
- For uncomplicated urogenital, anorectal, and pharyngeal gonococcal infection, a drug regimen using ceftriaxone plus either azithromycin or doxycycline may be used.