Question
Most specific test of Connective tissue disorder shown in Photograph
A. ssDNA
B. dsDNA
C. Anti-Smith antibody
D. Histones
Show Answer
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Correct Answer » C Explanation |
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Ans. C Anti-Smith antibody
(Disorder shown: SLE)
SLE is a chronic autoimmune disease that can affect almost any organ system; thus, its presentation and course are highly variable, ranging from indolent to fulminant.
In childhood-onset SLE, there are several clinical symptoms more commonly found than in adults, including malar rash, ulcers/mucocutaneous involvement, renal involvement, proteinuria, urinary cellular casts, seizures, thrombocytopenia, hemolytic anemia, fever, and lymphadenopathy.