Question
True regarding development of urogenital system is / are?
A. Urinary bladder trigone is derived from vesicourethral canal
B. Collecting duct originates from mesonephric duct
C. Sex cords are derived from coelomic epithelium
D. Differentiation of genital ridge into lineage of female or male gonads occurs at 10 weeks
E. Mesonephric duct is the main genital duct in males
Show Answer
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Correct Answer » B:C:D:E
Explanation
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Ans. B, C, D, E
The urinary bladder (except trigone) is derived from vesicourethral canal, cranial part of urogenital sinus (endodermal).
Trigone is derived from absorbed part of Wolfian duct / Mesonephric duct (mesodermal).
Ureteric bud, which arises from lower part of mesonephric duct, forms collecting part of kidney (pelvis, major calyes, minor calyes, collecting tubules) and ureter.
Coelomic epithelium on medial side of the mesonephros becomes thickened to form genital ridge, the site where ovary develops.
Genital ridge is covered by germinal epithelium (previous coelomic epithelium).
From these germinal epithelium, cords of cells (sex cords or medullary cords).
Differentiation of genital ridge into lineage of female or male gonads (ovary or testes) occurs at 6-10 weeks.
Mesonephric duct is the main genital duct in males as it gives rise to mainly male genital system