Question
True regarding red pulp of spleen is/are?
A. Periarteriolar lymphoid sheaths
B. B-cell containing lymphoid follicles
C. Perisinusoidal macrophages
D. Composed of sinusoids and splenic cords
E. Removal of old RBCs and modification of new cells
Show Answer
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Correct Answer » C:D:E
Explanation
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Ans. C, D & E
- Structure of splenic parenchyma
- The aggregations of T and B lymphocytes around the arterioles form White pulps or Malpighian bodies/corpuscles.
- T-cells in the center as periarteriolar lymphatic sheaths (PALs), B-cells containing lymphoid tissue in the middle, and dendritic presenting cells at periphery.
- Red pulp contains large number of venous sinusoids (splenic sinuses) draining into tributaries of splenic vein.
- Venous sinusoids are lined by endothelial stave cells which form incomplete layer and present intracellular slits between them through which blood can percholate.
