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Question

True regarding red pulp of spleen is/are?

A. Periarteriolar lymphoid sheaths

B. B-cell containing lymphoid follicles

C. Perisinusoidal macrophages

D. Composed of sinusoids and splenic cords

E. Removal of old RBCs and modification of new cells

 

Show Answer

Correct Answer » C:D:E

Explanation

Ans. C, D & E

  • Structure of splenic parenchyma
    • The aggregations of T and B lymphocytes around the arterioles form White pulps or Malpighian bodies/corpuscles.
    • T-cells in the center as periarteriolar lymphatic sheaths (PALs), B-cells containing lymphoid tissue in the  middle, and dendritic presenting cells at periphery.
    • Red pulp contains large number of venous sinusoids (splenic sinuses) draining into tributaries of splenic vein.
    • Venous sinusoids are lined by endothelial stave cells which form incomplete layer and present intracellular slits between them through which blood can percholate.
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