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Which of the following antibodies are found in neonatal lupus?

A. Anti U-1 RNP

B. Anti Ro-La

C. Anti M2 mitochondrial

D. Anti Smith antibodies

E. Anti-histone antibodies

Correct Answer » A:B Explanation

Ans. A & B
Neonatal lupus erythematosus (NLE) refers to a clinical spectrum of cutaneous, cardiac, and systemic abnormalities observed in newborn infants whose mothers have autoantibodies against Ro/SSA, La/SSB, and, less commonly, U1-ribonucleoprotein (U1- RNP).