Pgi Chandigarh – 83968

Regulatory T-cells?

A. Prevent autoimmune diseases

B. Activate other T & B cells

C. Suppress tumor immunity

D. Associated with CD25, CD4 & FOX P3

E. Associated with CD33, CD 117 & FOX L3

Correct Answer » A:C:D Explanation

A, C & D
Regulatory T-cells maintain tolerance to self-antigen, and prevent autoimmune disease
T helper cells (TH cells) (not the Regulatory T cells)assist other white blood cells in immunologic processes, including maturation of B cells into plasma cells and memory B cells, and activation of cytotoxic T cells and macrophages.
Regulatory T-cellsexpress the biomarkers CD4, FOXP3, and CD25
Regulatory T- cells are thought to suppress tumor immunity.