Question
True statement regarding proto-oncogene is/are?
A. Responsible for normal cell proliferation
B. Need some stimuli to get activated
C. Oncoproteins produced by oncogenes are nonspecific
D. Point mutation activates RAS
E. p53 is an important protooncogene
Show Answer
|
Correct Answer » A:B:D
Explanation
|
|
Ans. A, B & D
Protoncogenes are required for normal grow than proliferation.
When they are converted to oncogenes uncontrolled proliferation causes cancer.
They act under proper physiological stimuli.
Oncoproteins are specific proteins encoded by oncogenes.
RAS is the best example of protooncogenes activated by point mutation.
p53 is a turmor suppressor gene.
