Question
A patient diagnosed with Rheumatoid arthritis was on medications. After 2 years, he developed a blurring vision and was found to have corneal opacity. Which drug is most likely to cause this?
A. Sulfasalazine
B. Chloroquine
C. Methotrexate
D. Leflunomide
Show Answer
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Correct Answer » B
Explanation
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Ans: B. Chloroquine
In long-term chloroquine therapy Ocular complications were observed
>This therapy is usually used in patients with rheumatoid arthritis, lupus erythematosus, sarcoidosis, discoid lupus, and other chronic “collagen disease”.
>Retinal changes, corneal opacifications, blurring of vision are some complications seen in long term use of Chloroquine.
Ref:https://www.ncbi.nlm.nih.gov/pubmed/1427503
