Question
Which of the following statements regarding proteoglycans is true?
A. consist of a core protein with GAG chains attached.
B. GAG contain oxidized acid sugars
C. negative charges cause to radiate out from the protein
D. All of these
Show Answer
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Correct Answer » D
Explanation
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Ans-D. All of these
* Proteoglycans contain many long unbranched polysaccharide chains attached to a core protein.
* The polysaccharide chains, called glycosaminoglycans, are composed of repeating disaccharide units containing oxidized acid sugars (such as glucuronic acid), sulfated sugars, and N-acetylated amino sugars.
* The large number of negative charges causes the glycosaminoglycan chains to radiate out from the protein so that the overall structure resembles a bottlebrush.
The proteoglycans are essential parts of the extracellular matrix, the aqueous humor of the eye, secretions of mucus-producing cells, and cartilage.
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