Question
Genes involved in X-Linked SCID-
A. EGFR
B. CD23
C. IL6
D. IL2RG
Show Answer
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Correct Answer » D
Explanation
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Answer-D. IL2RG
* X-linked severe combined immunodeficiency (SCID) is an inherited disorder of the immune system that occurs almost exclusively in males.
* Mutations in the IL2RG gene cause X-linked SCID. The IL2RG gene provides instructions for making a protein that is critical for normal immune system function.
* Mutations in the IL2RG gene prevent these cells from developing and functioning normally. Without functional lymphocytes, the body is unable to fight off infections.
