Question
True about yθT cells:
A. Are helper t cells
B. Oligoclonal proliferation
C. Antigen presentation
D. Opsonization
Show Answer
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Correct Answer » B
Explanation
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Ans: B. Oligoclonal proliferation
| Cell Type |
Subset |
Main mediators |
Established role |
Findings in allergic rhinitis (AR) |
| γδ T cell |
* IFNγ
* IL-17A
* IL-17F
* IL-22
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* proinflammatory and immune-modulating functions at epithelial surfaces
* innate and adaptive immunity participation |
* yδT cytokines induce B cell IgE synthesis
* support Th2 inflammatory response
* oligoclonal proliferation in nasal mucosa (?)
* ↑ circulating yδT cell percentages correlating with Th17 numbers in AR
* negative correlation with Tregs
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