Question
Zero-order kinetics is otherwise known as saturation kinetics. It is independent of:
A. Plasma concentration
B. Clearance
C. Volume of distribution
D. Half life
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Correct Answer » A Explanation |
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Ans. A. Plasma concentration
- In zero-order kinetics or saturation kinetics, elimination mechanisms become saturated and unable to process more drugs when drug concentrations rise.
- Consequently, for drugs that are eliminated by zero-order kinetics, a constant amount of drug is eliminated per unit time regardless of drug plasma concentration.