Antiphospholipid antibody syndrome-Diagnosis
1. Arterial/ Venous Thrombosis (Superficial/Deep)
- ≥3 losses in <10 weeks 3. ≥1 loss in >10 weeks of morphologically normal fetus.
At least 1 Preterm delivery secondary to severe PIH/Uteroplacental insufficiency
- Presence of Lupus Anticoagulant (LAC)
Presence of IgM / IgG Cardiolipin Antibody Any of these should beresent@2occasions12wksapart
Presence of β2 Micro globulin
Note: In APLA – APTT is prolonged; PT is normal; Russel viper venom time is prolonged.