Blood brain barrier


Blood brain barrier


BBB Locations:

→ Formed by TIGHT JUNCTIONS & FOOT PROCESSES OF ASTROCYTES.

→ ABSENT BBB = CIRCUMVENTRICULAR ORGANS (mnemonic – SOAP)

S= Subfornical organ; O – Organum Vasculosum of Lamina Terminalis; A – Area Postrema; P – Posterior Pituitary

BBB Permeability:

PERMEABLE Substance:

Glucose (GLUT-1),

Water (Aquaporin-4),

Gases (CO2, O2, N2),

Lipid soluble hormones (Steroids)

NON-PERMEABLE Substance:

Protein Hormones,

• Dopamine (L-dopa in Parkinsonism),

H+ ions

Leave a Reply

%d bloggers like this:
Malcare WordPress Security