CANDIDIAL (MONILIAL) VAGINITIS

CANDIDIAL (MONILIAL) VAGINITIS


EPIDEMIOLOGY:

  • Candida albicans is the common cause of vaginitis.
  • Risk factors altering the immune response include
    • Pregnancy
    • Medications—Oral contraceptives( Monilial vaginitis), antibiotics, corticosteroids, cancer chemotherapy
    • HIV and other STDs
    • Diabetes mellitus(Vulval candidiasis )
    • Poor personal hygiene
    • Run down condition of health in general.

SIGNS AND SYMPTOMS:

Severity of the following symptoms varies between women and from time to time in the same woman.

  • Intense pruritis
  • White, “curdy” vaginal discharge, (resembles lumps of cottage cheese).
  • The odor may be unpleasant, but not foul.
  • Swollen, red, tender, itching vaginal lips (labia) and surrounding skin.
  • Burning on urination.
  • Change in vaginal color from pale pink to red.

DIAGNOSIS:

Clinical data

  • Complaints of pruritus, burning, dysuria
  • Evidence of vulvar erythema, oedema, scratch marks
  • Discharge: whitish, flaky or curd-like 
  • Vaginal pH : 4.5

INVESTIAGTIONS:

  •  KOH treated wet mount of the vaginal discharge helps to dissolve all cellular debris, leaving behind the resistant hyphae and spores of candida.

Culture:

  • Sabouraud’s agar—Presence of discrete creamy rounded colonies appear in 48–72 h, giving a typical yeast-like odour.
  • Nickerson’s Medium :Colonies appear in 48–72 h as brown-black discrete round colonies.

MANAGEMENT:

  • Preventive measures
    • Improve personal hygiene
    •  Discontinue offending medications
    • Control diabetes
  • Antifungal creams or pessaries for 7–14 days.Oral antifungal agents—Flucanazole – single oral dose of 150 mg.
    • Clotrimazole, Miconazole, Terconazole, Butoconazole
PREVENTIONS:
  • Avoid broad-spectrum antibiotics unless absolutely necessary.
  • Keep genital area clean. Use plain unscented soap.
  • Take showers rather than tub baths.
  • Wear cotton underpants or pantyhose with a cotton crotch.
  • Don’t sit around in wet clothing.
  • Avoid douches, vaginal deodorants and bubble baths.
  • Limit your intake of sweets and alcohol.
  • After urination or bowel movements, cleanse by wiping or washing from front to back (vagina to anus).
  • Lose weight if you are obese.
  • If you have diabetes, adhere to your treatment program.

Exam Important

  • Vaginal candidiasis is Associated with intense pruritus
  • Vaginal candidiasis shows Typical “Cottage cheese” discharge
  • Vulval candidiasis is associated with Diabetes mellitus
  • Vaginal candidiasis shows Buds and hyphae in KOH preparation
  • Oral contraceptives causes Monilial vaginitis
  • Diabetes mellitus, OCP user,Pregnancy & HIV are risk factor for vaginal candidiasis
  • Commonest fungal infection of the female genitalia in diabetes is Candidial infection
  • Treatment of both partners is not recomended in vaginal candidiasis
  • Genital infection in females presenting with thick curdy or flaky discharge may be Candidiasis
  • Candidal vaginitis  is most likely to be associated with vaginal pH of 4 
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