CARBON MONOXIDE POISONING
| A | Cyanosis | |
| B |
Cerebral edema |
|
| C |
Convulsions |
|
| D |
Bradycardia |
In CO poisoning all of the following clinical features are seen, EXCEPT:
| A |
Cyanosis |
|
| B |
Cerebral edema |
|
| C |
Convulsions |
|
| D |
Bradycardia |
Carbon monoxide (CO) is a colourless, odorless, tasteless, and non irritating gas produced by the incomplete combustion of any carbon-containing material.
CO binds to hemoglobin with an affinity 250 times that of oxygen, resulting in reduced oxyhemoglobin saturation and decreased blood oxygen-carrying capacity.
CO may also directly inhibit cytochrome oxidase, further disrupting cellular function, and it is known to bind to myoglobin, possibly contributing to impaired myocardial contractility.
Symptoms of intoxication are predominantly in organs with high oxygen consumption, such as the brain and heart.
| A | Cherry red colour | |
| B |
Cyanosis |
|
| C |
Petechial haemorrhage over conjunctiva |
|
| D |
Frothing at the mouth |
- Above 80% of COHb% causes rapid death from respiratory arrest.
- A cherry-red colouration of the skin, mucous membranes, conjunctiva, nail beds, areas of hypostasis, blood, tissues, and internal organs is seen in CO poisoning.
- This colour changes to dark-green, then to brown with the onset of decomposition.
Condition where severe hypoxaemia occurs without cyanosis
| A |
CO poisoning |
|
| B |
High altitude |
|
| C |
Anaemia |
|
| D |
A & C |
A i.e. CO poisoning C i.e Anemia
Which of the following statements about Carbon Monoxide poisoning is not true:
| A |
Carboxy haemoglobin (COHb) causes left shift of oxyhaemoglobin dissociation curve |
|
| B |
Partial pressuresas low as 0.6 mm Hg can be lethal |
|
| C |
Tissue toxicity plays an important role in clinical CO poisoning |
|
| D |
Hyperbaric oxygen is used for treatment |
C i.e. Tissue toxicity plays an important role in clinical CO poisoning
Diagnosis of CO poisoning post mortem
| A |
Blood thin and red coloured |
|
| B |
Congestion of all organs |
|
| C |
Cyanosis |
|
| D |
a and b |
A i.e. Blood is thin & red coloured; B i.e. Congestion of all organs;
Orthobaric oxygen is used in:-
| A |
CO poisoning |
|
| B |
Ventilation failure |
|
| C |
Anerobic infection |
|
| D |
Gangrene |
Ans is ‘a’ i.e., CO Poisoning
- Orthobaric Oxygen – 100% oxygen at atmospheric pressure.
- Orthobaric oxygen is used in CO poisoning. It reduces the half life of carboxyhemoglobin complex.
- About use of hyperbaric oxygen in CO poisoning.
– Although hyperbaric oxygen therapy is often recommended for patients with coma, syncope, seizures, and cardiovascular instability, for those who do not respond to orthobaric oxygen therapy, recent data suggest that it is no more effective than orthobaric oxygen therapy – [Harrison 15/e p 2660; CMDT 2005, p1572]
Anemic hypoxia is seen
CMC (Vellore) 14
| A |
CO poisoning |
|
| B |
CO2 poisoning |
|
| C |
HCN poisoning |
|
| D |
Nerve gas |
Ans. CO poisoning
Symptoms of CO poisoning starts when the concentration is:
| A |
< 10% |
|
| B |
> 10% |
|
| C |
> 20 % |
|
| D |
> 40 % |
Ans. > 10%
In CO poisoning, immediate emergency treatment:
Jharkhand 10
| A |
5% CO2 inhalation |
|
| B |
10% CO2 inhalation |
|
| C |
High flow O2 |
|
| D |
Nitroglycerine |
Ans. High flow O2
Hyperbaric oxygen is given in the treatment of:
Bihar 12
| A |
Nerve gas |
|
| B |
CO2 poisoning |
|
| C |
HCN poisoning |
|
| D |
CO poisoning |
Ans. CO poisoning
Postmortem finding in CO poisoning is:
UP 09; PGI 10
| A |
Cherry red hypostasis |
|
| B |
Intense cyanosis |
|
| C |
Excessive salivation |
|
| D |
Pin-point pupil |
Ans. Cherry red hypostasis
