PGI Chandigarh

Question Ketogenic amino acids are? A. Leucine B. Lysine C. Alanine D. Phenylalanine  E. Proline   Show Answer Correct Answer » A:C:D Explanation Ans. A, C & D Leucine and lysine ore purely ketogenic amino acids Alanine and proline are purely glucogenic amino acids Phenylalanine is both ketogenic as well as glucogenic.

Question Percentage of mitochondrial DNA out of total cellular DNA is? A. 1% B. 1.3% C. 3% D. 5% E. 10%   Show Answer Correct Answer » A Explanation Ans. A. In mammalian cells, only about 1% of the total cellular DNA is composed of mitochondrial DNA whereas in other organisms (for example in the

Question Which of the following are dangerous if given in more than 100mg per day dose? A. Vitamin A B. Vitamin B6 C. Vitamin C D. Vitamin D E. Vitamin E   Show Answer Correct Answer » A:B:D Explanation Ans. A, B & D Upper limit of daily intake i.e. Upper tolerable limit (W) of

Question True regarding glutathione conjugation is/are? A. N-glutathione transferase enzyme is the most important enzyme B. Cannot occur with out NAGS (N-acetylglutamate synthase) enzyme C. High expression of enzymes leads to decrease activity of anticancer drugs D. Glutathione transferase enzyme constitutes about 10% of soluble proteins in liver cells. E. An increased GSSG-to-GSH ratio is

Question Which of the following is not true regarding DNA? A. Pyrimidines are uracil and cytosine B. mRNA is a complimentary copy of template strand C. The genetic information resides in the non-coding strand D. Main form is right handed helix E. 3′-5‘ phosodiester bonding is present between two strands of DNA   Show Answer

Question All are true regarding proteosomes except? A. They are made up of proteins B. Require ATP to work C. Works in combination with ubiquitin protein D. Associated with degradation of plasma proteins E. All of the above   Show Answer Correct Answer » D Explanation Ans. D. Proteasomes are protein complexes which degrade unneeded

Question Urea cycle enzymes include? A. Carbamoyl phosphate synthase B. Argininosuccinase C. Ornithine transcarbamylase D. Argininosuccinate synthase E. All of the above   Show Answer Correct Answer » E Explanation Ans. E. Urea synthesis is a 5 step cyclic process, with 5 distinct enzymes. The first 2 enzymes are present in mitochondria while the rest are

Question Fatty acid synthesis cycle enzymes include? A. ATP -citrate lyase B. Acetyl Co-A carboxylase C. Glycerol -3- phosphate hydrogenase D. Acyl transacylase E. Glycerol kinase   Show Answer Correct Answer » A:B:D Explanation Ans. A, B & D. In cytosol, citrate is cleaved by ATP-citrate lyase to oxaloacetate and acetyl-CoA. Production of malonyl –

Question Unsaturated fatty acids are? A. Linoleic acid B. Linolenic acid C. Arachidonic acid D. Oleic acid  E. Palmitic acid   Show Answer Correct Answer » A:B:C Explanation Ans. A, B & C Alpha linoleaic acid Linoleic acid, Clupandonic acid Gama linolenic acid Nervonic acid Cervonic acid Arachidonic acid Oleic acid Elaidic acid Palmitoleic acid

Question Which of the following is a stop codon? A. UAC B. UCA C. UAG D. UGA  E. UAA   Show Answer Correct Answer » C:D:E Explanation Ans. C, D & E. UCA codes for serine, UAC encodes for tyrosine. Stop or termination or nonsense codons Three of the 64 possible nucleotide triplets UAA (amber),