PGI Chandigarh

Question Noonan syndrome is characterized by all except? A. Shield chest B. Short stature C. Involve gene is PTPN D. Increased carrying angle of elbow E. HOCM   Show Answer Correct Answer » A Explanation Ans. A Noonan syndrome is an autosomal dominant disorder which affects both females and males. Important features are short stature, […]

Question De-George syndrome is characterized by all except? A. Increased serum Ig E B. Hypocalcemia C. Thymic hyperplasia D. Hypothyroidism E. Lymphopenia   Show Answer Correct Answer » C Explanation Ans. C. The T cell lymphoma is seen much more in infancy than in adulthood. Atypical complete DiGeorge syndrome are primary immune deficiencies that are

Question Which of the following antibodies are found in neonatal lupus? A. Anti U-1 RNP B. Anti Ro-La C. Anti M2 mitochondrial D. Anti Smith antibodies E. Anti-histone antibodies   Show Answer Correct Answer » A:B Explanation Ans. A & B Neonatal lupus erythematosus (NLE) refers to a clinical spectrum of cutaneous, cardiac, and systemic

Question True regarding papillary carcinoma of thyroid is? A. Most common thyroid carcinoma B. Pre-laryngeal lymph nodes are called Delphian nodes C. Capsular invasion is common and diagnostic D. Hematogenous spread is common E. It has a better prognosis than follicular carcinoma thyroid   Show Answer Correct Answer » A:B:E Explanation Ans. A, B &

Question Mitochondrial matrix contains enzymes of? A. Pyruvate dehydrogenase B. ATP synthase C. Acyl CoA synthatase D. TCA cycle E. Beta oxidation   Show Answer Correct Answer » A:D:E Explanation A, D & E The enzymes in the matrix facilitate reactions responsible for the production of ATP, such as the citric acid cycle, oxidative phosphorylation,

Question Non-polar amino acids are? A. Arginine B. Asparginine C. Isoleucine D. Lysine  E. Proline   Show Answer Correct Answer » C:E Explanation CLASSIFICATION BASED ON SIDE CHAINAmino acids having nonpolar side chains: These include alanine, valine, leucine, isoleucine, methionine, proline, phenylalanine, and tryptophan. Amino acids having uncharged or nonionic polar side chains: glycine, serine, threonine,

Question The human plasma lipoprotein containing the highest percentage of triacylglycerol by weight is? A. LDL B. Chylomicrons C. VLDL D. HDL E. All have same quantity   Show Answer Correct Answer » B Explanation Ans. B. Maximum triglyceride content – Chylomicrons Maximum exogenous triglyceride – Chylomicrons Maximum endogenous triglyceride – VLDL Maximum cholesterol content

Question Hyperuricemia occurs due to? A. HGPRT deficiency B. UMP synthase deficiency C. PRPP deficiency D. Ornithine transcarbamylase deficiency E. Glucose-6-phosphate deficiency   Show Answer Correct Answer » A:E Explanation Ans. A & E HGpRT deficiency causes Lesch-Nyhan syndrome, characterized by hyperuricemia, gouty arthritis, urinary stones. UMP synthase deficiency results in Orotic aciduria. PRPP overactivity

Question Endoplasmic reticular proteins causing folding of protein? A. CYP 450 B. ERp57 C. Insulin receptors D. Protein disulphide isomerase E. Glucose related protein   Show Answer Correct Answer » B:D:E Explanation Ans. B, D & E The ER foldase ERp57 (ako known as Grp58) is a disulfide isomerase involved in the folding of a

Question Folate deficiency causes decrease in all of the following processes except? A. Conversion of creatine phosphate to creatinine B. All pyrimidine synthesis during RNA formation C. All pyrimidine synthesis for DNA formation D. Homocysteine to methionine E. Serine to glycine conversion   Show Answer Correct Answer » A:B:C Explanation Ans. A, B & C