Causes of isolated spontaneous abortion

The causes for isolated spontaneous abortion in 1st & 2nd trimester include:

Chromosomal abnormalities:

1.Aneuploidy M/C

2.Trisomy – 2nd best answer

3.Monosomy X (20%)- 3rd

4.Trisomy 16 (16%)

Germ plasm defects

Fetal causes

• Weather it is first or second trimester the m/c cause is chromosomal abnormality.

The frequency of abortion during 1st trimester is 50% and during 2nd is 35%