CLINICAL MONITORING OF ANESTHESIA

CLINICAL MONITORING OF ANESTHESIA

Q. 1 Train of four fade is a characteristic feature of:

 A Depolarizing block

 B

Non depolarizing block

 C

Both depolarizing and non-depolarizing block

 D

Malignant hyperthermia

Q. 1

Train of four fade is a characteristic feature of:

 A

Depolarizing block

 B

Non depolarizing block

 C

Both depolarizing and non-depolarizing block

 D

Malignant hyperthermia

Ans. B

Explanation:

Train of four fade is a characteristic of a non-depolarizing block.

The Train-of-four stimulation denotes the administration of four successive 200-ps stimuli in 2 seconds (2 Hz) and

a series of patterns are produced and these patterns differ in a depolarizing block differs from that of a non-depolarizing block.

In a non-depolarizing block there is progressive depression of height with each twitch (fade) and in a depolarizing block there is equal depression of all four twitches (No fade).

Ref: Clinical Anesthesiology By G. Edward Morgan, 4th Edition, Pages 152, 209


Q. 2

All of the following statements about neuromuscular blockage produced by succinylcholine are true, except:

 A

No fade on Train of four stimulation

 B

Fade on tetanic stimulation

 C

No post tetanic facilitation

 D

Train of four ratio > 0.4

Ans. B

Explanation:

Succinylcholine is a depolarizing neuromuscular blocker.

With succinylcholine no fading is observed after train of four or tetanic stimulation.

All four stimulatory responses after TOF stimulation are suppressed to the same extent.

 
Ref: Neuromuscular Monitoring in Clinical Practice and Research By Thomas Fuchs-Buder, Page 16

Q. 3

For non depolarization block which of the following statement is correct

 A

Post tetanic potentiation is seen

 B

Tetanic fade is absent

 C

Train of four is absent

 D

Anticholinergic drugs potentiation of block

Ans. A

Explanation:

A i.e. Post titanic potentiation is seen



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