Major depressive episode in absence of any manic, mixed or hypomanic episode

One of the commonest psychiatric disorder [Lifetime prevalence 17%]

Twice as prevalent in Women, Mean Age = 40 Years

Responsible for Maximum DALY [Disability Adjusted Life Years]

Most common cause of Suicide

More commonly seen in divorced and separated persons

Endogenous Vs Exogenous [Reactive] Depression

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