Etiopathogenesis of schizophrenia-Biochemical factors


Etiopathogenesis of schizophrenia-Biochemical factors


The etiopathogenesis of schizophrenia consists of following factors:

  • Genetic
  • Biochemical
  • Neuropathological

Biochemical factors:

Dopamine Hypothesis – Excess of dopaminergic activity

Serotonin – Currently along with dopamine excess of serotonin is also considered

Other Neurotransmitter – GABA, NE, Ach, Nicotine, Glutamate

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