Ketone bodies-Clinical aspects

Ketone bodies-Clinical aspects

→ Ketonemia – Ketone body in Blood

→ Ketonuria – Ketone Body in Urine

→ Ketosis = Ketonemia + Ketonuria

→ Ketone Body has protective effect on breakdown of structural proteins

→ They Can cause Metabolic Acidosis with High Anion Gap and Hyperkalemia

→ Hyperkalemia due to inhibition of Na/K Pump due to depletion of Alkali Reserve of the Body

→ Ketogenic Diet – High Fat, Adequate Protein and Low Carbohydrate

→ Use of Ketogenic Diet – Weigh Reduction [Atkin Diet] and Refractory Epilepsy

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