Lathyrism
| A | Aflatoxin | |
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
An agricultural labourer presented with progressive spastic paralysis is diagnosed of having neurolathyrism. It results from consumption of:
| A |
Aflatoxin |
|
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
BOAA is
| A |
Beta-oxalyl amino alanine |
|
| B |
Beta-oxalo acetoacetate |
|
| C |
Beta-oxalyl aminoacetate |
|
| D |
Beta-oxalyl acetylacetate |
Ans. is ‘a’ i.e., Beta-oxyaly amino alanine
BOAA stands for Beta-oxalyl-amino alanine.
BOAA causes Lathyrism.
- Lathyrism is a paralysing disease of humans and animals.
In humans, it affects the nervous system — Neurolathyrism.
- In animals, it affects the skeletal system —Osteolathyrism
Neurolathyrism
The disease affects young men between 15-45 years.
- It is characterized by spastic paralysis of lower limbs.
interventions for prevention and control
Vitamin C prophylaxis
Banning the crop
Removal of toxin: Steeping method and Parboiling
Education
Genetic approach
Socio-economic changes
| A |
Aflatoxin |
|
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
Ans. is ‘b’ i.e., BOAA
- Lathyrism is caused by Lathyrus sativus, commonly known as “Khesari dhal”.
o The toxin present in Lathyrus seeds has been identified as Beta oxalyl amino alanine (BOAA).
True about lathyrism:
PGI 09
| A |
Caused by Aspergillus flavus |
|
| B |
Prevented by parboiling |
|
| C |
Sanguinarine is the toxic principle |
|
| D |
All |
Ans. Patient develops spastic paraplegia
Neurolathyrism is due to ‑
| A |
Argemone oil |
|
| B |
Jhunjhunia |
|
| C |
Khesari dal |
|
| D |
None |
Ans. is ‘c’ i.e., Khesari dal
