Corrosives Poisoning: Magenstrasse
Introduction
- corrosives Poisoning: Magenstrasse(the gastric cannal or furrow)
- It is a groove in the stomach along the lesser curvature that is the route food and liquids tend to take in moving toward the pylorus and that is a frequent site of peptic ulcer formation.
Corrosives fix, destroy and erode the surface with which they come in contact. They mainly act locally by
- Hygroscopic: Extraction of water from tissues,
- Coagulation of proteins and
- Conversion of haemoglobin into hematin.
As a rule there is no remote systemic action with exception to shock. Corrosives are:
- Mineral acid: Sulphuric acid (H2SO4), nitric acid, hydrochloric acid.
- Organic acid: Oxalic acid, carbolic acid, salicylic acid, acetic acid.
- Vegetable acid: Hydrocyanic acid.
- Alkalis: Caustic potash, caustic soda, ammonium hydroxide.
- Magenstrasse is the term applied to the pathway acidic agents follow in stomach.
- The pathway of acids and alkalis in food filled stomach starts along the lesser curvature of the stomach and leads to the pylorus.
- This explains the location of greatest damage in food filled stomach.
- Stomach without food have significant injury in the lower half of two thirds and may have sparing of fundus.

Exam Important
- Magenstrasse is the term applied to the pathway acidic agents follow in stomach.
- The pathway of acids and alkalis in food filled stomach starts along the lesser curvature of the stomach and leads to the pylorus.
- This explains the location of greatest damage in food filled stomach.
- Stomach without food have significant injury in the lower half of two thirds and may have sparing of fundus.
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