- Phosphorus is a protoplasmic poison affecting cellular oxidation and causing anoxic necorbiosis, classically affecting liver.
- It increases fat deposition and inhibits glycogen deposition in liver. It is used in fire works (Diwali poisoning) and as rat poison. Lethal dose is 60-120 mg.
- Earliar CuSO4 was used as an antidote for phosphorous poisoning.
Phosphorus occurs in two forms:
- It is white, and becomes yellow on exposure to air.
- It is translucent, luminous and crystalline cylinders.
- It has garlic like odor. It is insoluble in water and luminous in dark.
- Its fumes show phosphorescence.
- It is reddish brown, inert, odourless and tasteless.
- It is nontoxic (thus poisoning occurs only due to white phosphorus.
- It is put on the sides (striking surface) of match box (along with powdered glass).
First stage: (GI irritation): There is nausea, vomiting, diarrhea and garlic odor. This stage lasts for 8 hours to 3 days.
Second Stage (Asymptomatic) : This stage lasts for 3 days.
- There is liver and kidney damage due to absorbed phosphorus.
- Initially liver is enlarged due to acute fatty infiItration.
- Later liver shrinks due to necrosis, i.e. Acute yellow atrophy.
- Toothache is the first symptom which is associated with loosening of teeth, necrosis of gums and osteomyelitis of jaw.
- Therefore chronic phosphorus poisoning is also known as Phossy jaw or glass jaw.
- There is garlic odor. viscera and stool glow in dark (due to luminosity).
- To preserve luminosity, viscera are preserved in saturated saline solution Rectified spirit is not used as it causes loss of Iuminosity.
- Acute yellow atrophy.
- liver and kidney damage
- Phossy jaw or glass jaw.
- There is garlic odor. viscera and stool glow in dark (due to luminosity)