Question
Secondary syphilis is characterized by all of the following except:
| A. |
Generalised mucocutaneous lesions
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| B. |
Generalised tender lymphadenopathy
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| C. |
Constitutional symptoms like fever and weight loss
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| D. |
Painless silver-grey mucosal erosions
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Show Answer
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Correct Answer » B
Explanation
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Secondary syphilis occurs 4–10 weeks after the primary chancre, due to hematogenous spread of Treponema pallidum. It is systemic, involving skin, mucous membranes, and lymph nodes.
Hallmark Features of Secondary Syphilis
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Generalised non-tender lymphadenopathy
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Maculopapular rash involving palms and soles
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Mucous patches (painless, silver-grey erosions)
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Condylomata lata (broad-based, moist papules)
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Constitutional symptoms (fever, malaise, weight loss)
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Lesions are highly infectious
Lymphadenopathy in secondary syphilis is generalised, firm, rubbery, and non-tender.
Tender nodes suggest acute bacterial infections, not syphilis.
Syphilis lymph nodes = non-tender at all stages (primary and secondary)
