Question
Commonest carcinoma that can cause splenic metastasis is which of the following?
| A. |
Ca. Pancreas
|
| B. |
Ca. Stomach
|
| C. |
Ca. Ovary
|
| D. |
Ca. Cervix
|
Show Answer
|
Correct Answer » C
Explanation
|
|
- Carcinoma ovary is the most common carcinoma associated with splenic metastasis among the given options.
- Ovarian carcinoma commonly spreads by:
- Transcoelomic (peritoneal) dissemination.
- Direct extension to the splenic capsule.
- Hematogenous spread in advanced disease.
- Splenic involvement is frequently seen in advanced epithelial ovarian carcinoma, especially involving the splenic capsule.
Why Other Options are Incorrect
A. Carcinoma pancreas
- Pancreatic carcinoma may directly invade the spleen, particularly tumors of the pancreatic tail.
- However, it is less commonly associated with true splenic metastasis than ovarian carcinoma.
B. Carcinoma stomach
- Gastric carcinoma usually spreads to:
- Liver
- Peritoneum
- Regional lymph nodes
- Splenic metastasis is uncommon.
D. Carcinoma cervix
- Cervical carcinoma commonly metastasizes to:
- Pelvic lymph nodes
- Para-aortic lymph nodes
- Lung
- Liver
- Bone
- Splenic metastasis is very rare.
