Question
Muscle most resistant to non-depolarizing block is:
| A. |
Diaphragm
|
| B. |
Ocular
|
| C. |
Adductor pollicis
|
| D. |
Intercostal muscles
|
Show Answer
|
Correct Answer » A
Explanation
|
|
- The diaphragm is the most resistant (least sensitive) skeletal muscle to non-depolarizing neuromuscular blocking agents.
- It requires a higher concentration of the drug to become paralyzed.
- Therefore, it is the last muscle to be paralyzed and the first muscle to recover during reversal of neuromuscular blockade.
Why Other Options Are Incorrect
B. Extraocular (Ocular) Muscles
- Incorrect because they are the most sensitive muscles to non-depolarizing neuromuscular blockers.
- They are among the first muscles to become paralyzed.
C. Adductor Pollicis
- Incorrect because it is more sensitive than the diaphragm.
- It is commonly used for Train-of-Four (TOF) monitoring, but it is not the most resistant muscle.
D. Intercostal Muscles
- Incorrect because they are less resistant than the diaphragm.
- They become paralyzed before the diaphragm during neuromuscular blockade.
