Question
One of the following is Common irreversible cause of dementia :
| A. |
Toxic dementia |
| B. |
Alzheimer’s ds. |
| C. |
Multi-infarct dementia |
| D. |
Pick’s disease |
|
Correct Answer » B Explanation |
 |
Correct Answer: B. Alzheimer’s disease
Detailed Explanation:
Clinical reasoning for the correct answer:
– Alzheimer’s disease is a progressive neurodegenerative disorder causing irreversible dementia.
– It is characterized by amyloid plaques and neurofibrillary tangles leading to irreversible neuronal loss.
– There is no current cure or reversal, only symptomatic management.
Why Option A is incorrect:
– Toxic dementia is caused by reversible factors such as drug intoxication or metabolic disturbances.
– Removing the toxin or treating the underlying cause often resolves or improves cognitive impairment.
– Examples include alcohol-related dementia and heavy metal poisoning.
Why Option C is incorrect:
– Multi-infarct dementia results from multiple ischemic strokes affecting cognition.
– While cognitive decline can be chronic, preventing further strokes and managing risk factors may partially stabilize or improve symptoms.
– Some improvement possible with rehabilitation.
Why Option D is incorrect:
– Pick’s disease (frontotemporal dementia) is a progressive and irreversible neurodegenerative disorder like Alzheimer’s disease.
– However, Alzheimer’s disease is a more common and prototypical irreversible dementia.
– Pick’s disease is irreversible but less common than Alzheimer’s; if a single answer must be selected, Alzheimer’s disease remains the best choice due to prevalence and classical teaching.
Note: Both Alzheimer’s disease and Pick’s disease are irreversible, but Alzheimer’s disease is often considered the prototypical irreversible dementia in clinical MCQs.
