Question
What is the approximate fatal dose of potassium cyanide (KCN) in humans?
| A. |
5 mg
|
| B. |
10 mg
|
| C. |
20 mg
|
| D. |
200 mg
|
Show Answer
|
Correct Answer » D
Explanation
|
|
- Potassium cyanide (KCN) is a highly lethal poison that inhibits cytochrome oxidase (Complex IV) in mitochondria.
- This blocks cellular respiration, leading to histotoxic hypoxia (cells cannot utilize oxygen).
Fatal Dose
- The commonly accepted fatal dose of potassium cyanide:
- Even smaller doses can be fatal depending on:
- Route (ingestion, inhalation)
- Individual susceptibility
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