Question
Drug of choice for Epilepsy in pregnancy is –
| A. |
Carbamazepine
|
| B. |
Sodium valproate
|
| C. |
Phenobarbitone
|
| D. |
Phenytoin
|
Show Answer
|
Correct Answer » A
Explanation
|
|
- Sodium valproate has the highest concern for teratogenicity, particularly neural tube defects and adverse neurodevelopmental outcomes, and should generally be avoided in pregnancy when alternatives are available.
- Phenytoin is associated with fetal hydantoin syndrome.
- Phenobarbitone also carries fetal risks.
- Carbamazepine, although not completely risk-free, is comparatively safer among these options in traditional exam-based questions.