Question
With help of the drug shown below, serotonin is synthesized from which of the following precursor amino acid?
| A. |
Tyrosine.
|
| B. |
Tryptophan.
|
| C. |
Phenylalanine.
|
| D. |
Glycine.
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Show Answer
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Correct Answer � B
Explanation
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|
Ans:B.)Tryptophan.
- Serotonin is synthesized from the essential amino acid tryptophan.
- The rate-limiting step is the conversion of the amino acid to 5-hydroxytrptophan by tryptophan hydroxylase.
- This is then converted to serotonin by the aromatic L-amino acid decarboxylase which needs Pyridoxal Phosphate as a cofactor.
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