Question
In the following type of graph as shown in the image,what is the cause for the shape of the graph for the fetus?
| A. |
High Hemoglobin Concentration
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| B. |
High Oxygen Concentration
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| C. |
Inability to bind 2,3 DPG
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| D. |
All of the above
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Show Answer
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Correct Answer � C
Explanation
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Ans:C.)Inability to bind 2,3 DPG
Oxygen Dissociation Curve of Maternal versus Fetal is shown in the image.
- Fetal Hemoglobin has higher affinity to O2 so as to obtain O2 from maternal blood in the placenta.
- The high oxygen affinity of fetal blood (HbF:α2γ2) is due to the inability of gamma chains to bind 2,3-BPG.
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