Question
A 30-years-old male patient presents with a history of heartburn. An upper GI endoscopy was done and a biopsy from a suspicious lesion showed the following picture. What does this show? Which special stains will you do for confirmation and what will you look for?

| A. |
H. pylori infection, Silver stain, Gram-negative coccobacilli |
| B. |
Adenocarcinoma esophagus, mucin stain, mitotic figures |
| C. |
Squamous cell carcinoma, keratin stain |
| D. |
Barrett’s esophagus, mucin stain, dysplasia |
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