Ans.B – Serum Ceruloplasmin
The image represents “Kayser-Fleischer” ring.
KF ring is a golden brown ring due to the deposition of copper in Descemet’s membrane of the cornea.
Clinical feature of “Wilson’s disease”-
Rare autosomal recessive disease.
Characterized by abnormal copper metabolism.
The deposition of copper in the posterior capsule of the lens results in sunflower cataract.
Presence of KF rings
Decreased serum ceruloplasmin (copper-containing enzyme/ferroxidase) levels
Measuring hepatic copper levels in liver biopsy
24-Hr urine copper excretion
Kayser Fleischer ring:
Excess circulating copper deposits in Descemet’s membrane.
Usually, golden brown is located in the peripheral cornea, beginning at Schwalbe’s line up to 5 mm into the cornea.
Detected via Gonioscopy in an earlier stage & seen by naked eyes in an advanced stage.