MCQ – 83618

Correct Answer � B Explanation

Ans.B – Serum Ceruloplasmin 

The image represents “Kayser-Fleischer” ring.

KF ring is a golden brown ring due to the deposition of copper in Descemet’s membrane of the cornea.

Clinical feature of “Wilson’s disease”-

Wilson’s Disease:

• Rare autosomal recessive disease.

• Characterized by abnormal copper metabolism.

Ophthalmic presentation:

• The deposition of copper in the posterior capsule of the lens results in sunflower cataract.

Diagnosis:

Sternlieb’s criteria:

• Presence of KF rings

• Decreased serum ceruloplasmin (copper-containing enzyme/ferroxidase) levels

• Measuring hepatic copper levels in liver biopsy

• 24-Hr urine copper excretion

Kayser Fleischer ring:

• Excess circulating copper deposits in Descemet’s membrane.

• Usually, golden brown is located in the peripheral cornea, beginning at Schwalbe’s line up to 5 mm into the cornea.

• Detected via Gonioscopy in an earlier stage & seen by naked eyes in an advanced stage.