Question
Which enzyme is common to both gluconeogenesis and glycolysis pathway?
| A. |
Glucokinase
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| B. |
Phosphofructokinase
|
| C. |
Pyruvate kinase
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| D. |
Phosphoglycerate kinase
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Show Answer
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Correct Answer � D
Explanation
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|
Ans.D. Phosphoglycerate kinase
- Seven of the reactions of glycolysis are reversible and are used in the synthesis of glucose by gluconeogenesis. Thus, seven enzymes are common to both glycolysis and gluconeogenesis.
- (i) Phosphohexose isomerase; (ii) Aldolase; (iii) Phosphotriose isomerase; (iv) Glyceraldehyde 3-phosphate dehydrogenase; (v) Phosphoglycerate kinase; (vi) Phosphoglycerate mutase; (vii) Enolase.
- Three of the reactions of glycolysis are irreversible and must be circumvented by four special reactions which are unique to gluconeogenesis and catalyzed by : (i) Pyruvate carboxylase, (ii) PEP carboxykinase, (iii) Fructose-1, 6- bisphosphatase, (iv) Glucose-6-phosphatase.
