Question
Sub-periosteal new bone deposition occurs in all except:
| A. | Hyperparathyroidism |
| B. |
Fluorosis |
| C. |
Caffey’s disease |
| D. |
All of the above |
Show Answer
|
Correct Answer � A Explanation |
 |
Hyperparathyroidism is associated with sub-periosteal bone resorption and not new bone formation.
The sub-periosteal new bone deposition is an important feature of both fluorosis and Caffey’s disease.
Caffey disease
- Caffey disease or infantile cortical hyperostosis is a largely self-limiting disorder which affects infants. It causes bone changes, soft-tissue swelling, and irritability.
- It is distinct from physiological periostitis which can be seen involving the diaphyses of the tibiae, humeri, and femora at the same age.
- A rare variant known as prenatal onset cortical hyperostosis is severe and fatal, though it is probably a separate entity altogether.
Radiographic features
- periosteal reaction, either single-layered or lamellated
- subperiosteal cortical hyperostosis
- dense laminated subperiosteal new bone formation
- marked increase in cortical width and density
- in the involved long bones, only the diaphysis is affected, sparing the metaphysis and epiphysis; consequently, the bone becomes spindle-shaped
- soft tissue swelling over the involved bones
- the mandible, clavicle, and ribs are most often affected, particularly in sporadic cases.
Fluorosis
- Skeletal fluorosis is a chronic metabolic bone disease caused by ingestion of large amounts of fluoride through either water or food in geographic areas where high levels of fluoride occur naturally.
Radiographic features
- increased bone density: osteosclerosis
- osteopenia or osteoporosis
- trabecular blurring or haziness
- compact bone thickening
- periosteal bone formation
- ossification of the attachments of tendons, ligaments, and muscles
- interosseous membrane calcification
- ossification of the posterior longitudinal ligament
Hyperparathyroidism is associated with sub-periosteal bone resorption and not new bone formation.
The sub-periosteal new bone deposition is an important feature of both fluorosis and Caffey’s disease.Caffey disease
- Caffey disease or infantile cortical hyperostosis is a largely self-limiting disorder which affects infants. It causes bone changes, soft-tissue swelling, and irritability.
- It is distinct from physiological periostitis which can be seen involving the diaphyses of the tibiae, humeri, and femora at the same age.
- A rare variant known as prenatal onset cortical hyperostosis is severe and fatal, though it is probably a separate entity altogether.
Radiographic features
- periosteal reaction, either single-layered or lamellated
- subperiosteal cortical hyperostosis
- dense laminated subperiosteal new bone formation
- marked increase in cortical width and density
- in the involved long bones, only the diaphysis is affected, sparing the metaphysis and epiphysis; consequently, the bone becomes spindle-shaped
- soft tissue swelling over the involved bones
- the mandible, clavicle, and ribs are most often affected, particularly in sporadic cases.
Fluorosis
- Skeletal fluorosis is a chronic metabolic bone disease caused by ingestion of large amounts of fluoride through either water or food in geographic areas where high levels of fluoride occur naturally.
Radiographic features
- increased bone density: osteosclerosis
- osteopenia or osteoporosis
- trabecular blurring or haziness
- compact bone thickening
- periosteal bone formation
- ossification of the attachments of tendons, ligaments, and muscles
- interosseous membrane calcification
- ossification of the posterior longitudinal ligament