Question
Which one of the following organisms, transmitted by rats is notable for its ability to grow in the bacillary phase or as naturally occurring cell-wall deficient L forms?
| A. |
Leptospira icterohaemorrhagiae
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| B. |
Rickettsia mooseri
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| C. |
Spirillum minus
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| D. |
Streptobacillus moniliformis
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Show Answer
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Correct Answer � D
Explanation
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Ans.D. Streptobacillus moniliformis
Streptobacillus moniliformis is present in the mouth of the wild rat and is transmitted to man by a rat bite (one form of rat bite fever) or by consumption of rat contaminated milk (Haverhill fever). The name is derived from its tendency in culture to grow as a mixture of chaining Gram negative bacilli interspersed with a yeast-like mass of swollen filaments and globular forms, often filled with minute granules.
This globular form, first described by Klieneberger as the symbiotic growth of a pleuropneumonia-like-organism (PPLO) was later recognized by Dienes as a cell wall deficient bacterial phase usually capable of reversion to the bacillary form. Thus the term L form was introduced after the Lister Institute where Klieneberger made her discovery.