Question
A 38-year-old white woman with multiple sclerosis was recently switched to a new medication for this disease. She now notes decreased vision in her right eye for one week. The new medication most likely associated with her visual change is:
| A. |
interferon-β1-b
|
| B. |
dimethyl fumarate
|
| C. |
fingolimod
|
| D. |
glatiramer acetate
|
Show Answer
|
Correct Answer � C
Explanation
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|
Answer: C. Fingolimod
Explanation: Fingolimod (Gilenya) is a new oral agent used to treat multiple sclerosis. It has been associated with macular edema in 0.4% of patients using the medication, with a higher risk seen in patients with a history of diabetes or prior uveitis. Macular edema usually appears within the first 4 months of starting the medication, and a screening examination is recommended prior to or within the first few weeks of starting the medication. The other medications have not been associated with significant ocular side effects.
