Question
A 48-year-old man is referred to an endocrinologist for newly diagnosed diabetes. He had elevated fasting serum glucose level a week earlier. The endocrinologist discusses the different treatment options available, including oral and injectable medications. He recommends treatment with an oral medication that alters glucose metabolism within the liver and explains that the liver is an important site for glucose regulation. Liver cells that shows high concentration of fructose 2,6-bisphosphate will have a low rate of conversion involving which of the following:
| A. |
Acetyl CoA → Fatty acids |
| B. |
Glucose → glycogen |
| C. |
Alanine → glucose |
| D. |
α-Ketoglutarate → glutamate |
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