Question
In a complete mole, which of the following statements are true? A. Serum Beta hCG level is hugely elevated. B. The urine pregnancy test is false negative. C. Serum free T4 levels rapidly normalize after uterine evacuation.
| A. |
A and C
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| B. |
A and B
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| C. |
A, B and C
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| D. |
B and C
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Show Answer
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Correct Answer � C
Explanation
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Ans. C
Statements A, B, and C are true.
In a complete molar pregnancy, serum β-hCG levels are commonly elevated above those expected for gestational age. An excessive β-hCG hormone causes an oversaturation of the test assay. This is because the sensitivity of most hCG tests is set to the pregnancy hCG range. These high values can lead to erroneous false-negative urine pregnancy test results. This is called the hook effect.
The thyrotropin-like effects of hCG frequently cause serum free T4 levels to be elevated. These levels rapidly normalize after the uterine evacuation.
