Question
If the volume of fetomaternal hemorrhage is greater than 30 mL whole blood, the dose of Rh-immunoglobulin calculated is
| A. |
10 μg for every 0.5 mL of fetal RBCs
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| B. |
10 μg for every 5 mL of fetal RBCs
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| C. |
0.5 μg for every 1 mL of fetal whole blood
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| D. |
5 μg for every 10 mL of fetal whole bloo
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Show Answer
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Correct Answer � A
Explanation
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Ans. A
If the volume of fetomaternal hemorrhage is greater than 30 mL whole blood, the dose of Rh-immune globulin calculated is 10 μg for every 0.5 mL of fetal RBCs.
Calculation is made as follows
300 microgram of Anti D can neutralise 15 ml of fetal RBCs or 30ml of fetal whole blood
50 microgram of Anti D can neutralise 2.5 ml of fetal RBCs
Half life of anti D is 16 -24 days
Route : Intramuscular either in deltoid / antero lateral aspect of thigh.