Question
A 45-year-old woman is brought to the emergency room after experiencing a generalized seizure. An X-ray film of the skull reveals a lytic bone mass. A CBC is normal. A portion of the skull and the adherent mass are removed. Microscopic examination of the surgical specimen is shown in the image. What is the appropriate diagnosis?
| A. |
Glioblastoma multiforme
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| B. |
Hemangioblastoma
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| C. |
Medulloblastoma
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| D. |
Meningioma
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Show Answer
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Correct Answer � C
Explanation
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Answer : C Medulloblastoma
Meningiomas are benign intracranial tumors that arise from the arachnoid villi and produce symptoms by compressing adjacent brain tissue.
They account for almost 20% of all primary intracranial neoplasms.
Meningiomas occur at almost any intracranial site but are most common in parasagittal regions of the cerebral hemispheres, the olfactory groove, and the lateral sphenoid wing.
On gross examination, most meningiomas appear as well-circumscribed, firm, bosselated masses of variable size.
The histologic hallmark of meningiomas is a whorled pattern of “meningothelial” cells.
The indolent growth of meningiomas enables them to enlarge slowly for years before becoming symptomatic, during which time they displace the brain but do not infi ltrate it. Although benign, meningiomas have a propensity to erode contiguous bone.
